Frailty in old age is associated with decreased interleukin-12/23 production in response to toll-like receptor ligation.

Frailty in old age is associated with decreased interleukin-12/23 production in response to toll-like receptor ligation.

Aging is associated with progressive alterations of immune functions, leading to higher susceptibility to bacterial and viral infections and reduced vaccine responses. Data concerning cytokine production in response to Toll-like receptor (TLR) ligands are highly variable in old people, reflecting th...

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Bibliographic Details
Main Authors: Nathalie Compté, Karim Zouaoui Boudjeltia, Michel Vanhaeverbeek, Sandra De Breucker, Joel Tassignon, Anne Trelcat, Thierry Pepersack, Stanislas Goriely
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3673922?pdf=render

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http://europepmc.org/articles/PMC3673922?pdf=render

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