Segregationally stabilised plasmids improve production of commodity chemicals in glucose-limited continuous fermentation

Abstract Background The production of chemicals via bio-based routes is held back by limited easy-to-use stabilisation systems. A wide range of plasmid stabilisation mechanisms can be found in the literature, however, how these mechanisms effect genetic stability and how host strains still revert to...

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Bibliographic Details
Main Authors: James R. Allen, Mario A. Torres-Acosta, Naresh Mohan, Gary J. Lye, John M. Ward
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Microbial Cell Factories
Subjects:
Online Access:https://doi.org/10.1186/s12934-022-01958-3