Segregationally stabilised plasmids improve production of commodity chemicals in glucose-limited continuous fermentation
Abstract Background The production of chemicals via bio-based routes is held back by limited easy-to-use stabilisation systems. A wide range of plasmid stabilisation mechanisms can be found in the literature, however, how these mechanisms effect genetic stability and how host strains still revert to...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-11-01
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Series: | Microbial Cell Factories |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12934-022-01958-3 |