Attenuated Mycobacterium tuberculosis vaccine protection in a low-dose murine challenge model

Attenuated Mycobacterium tuberculosis vaccine protection in a low-dose murine challenge model

Summary: Bacillus Calmette–Guérin (BCG) remains the only approved tuberculosis (TB) vaccine despite limited efficacy. Preclinical studies of next-generation TB vaccines typically use a murine aerosol model with a supraphysiologic challenge dose. Here, we show that the protective efficacy of a live a...

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Bibliografski detalji
Glavni autori: Samuel J. Vidal, Daniel Sellers, Jingyou Yu, Shoko Wakabayashi, Jaimie Sixsmith, Malika Aid, Julia Barrett, Sage F. Stevens, Xiaowen Liu, Wenjun Li, Courtney R. Plumlee, Kevin B. Urdahl, Amanda J. Martinot, Dan H. Barouch
Format: Članak
Jezik:English
Izdano: Elsevier 2023-06-01
Serija:iScience
Teme:
Immunology
Medical microbiology
Online pristup:http://www.sciencedirect.com/science/article/pii/S2589004223010404

Internet

http://www.sciencedirect.com/science/article/pii/S2589004223010404

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