Methionine aminopeptidase 2 and its autoproteolysis product have different binding sites on the ribosome
Abstract Excision of the initiator methionine is among the first co-translational processes that occur at the ribosome. While this crucial step in protein maturation is executed by two types of methionine aminopeptidases in eukaryotes (MAP1 and MAP2), additional roles in disease and translational re...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-01-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-024-44862-7 |