S100A12 Expression Is Modulated During Monocyte Differentiation and Reflects Periodontitis Severity

S100A12 is a calcium-binding protein of the S100 subfamily of myeloid-related proteins that acts as an alarmin to induce a pro-inflammatory innate immune response. It has been linked to several chronic inflammatory diseases, however its role in the common oral immunopathology periodontitis is largel...

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Main Authors: Ronaldo Lira-Junior, Sofia Björnfot Holmström, Reuben Clark, Stephanie Zwicker, Mirjam Majster, Gunnar Johannsen, Björn Axtelius, Sigvard Åkerman, Mattias Svensson, Björn Klinge, Elisabeth A. Boström
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00086/full