Comparing ATPase activity of ATP-binding cassette subfamily C member 4, lamprey CFTR, and human CFTR using an antimony-phosphomolybdate assay

Comparing ATPase activity of ATP-binding cassette subfamily C member 4, lamprey CFTR, and human CFTR using an antimony-phosphomolybdate assay

Introduction: ATP-binding cassette (ABC) transporters use the hydrolysis of ATP to power the active transport of molecules, but paradoxically the cystic fibrosis transmembrane regulator (CFTR, ABCC7) forms an ion channel. We previously showed that ATP-binding cassette subfamily C member 4 (ABCC4) is...

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Bibliographic Details
Main Authors: Guiying Cui, Kerry M. Strickland, Analia J. Vazquez Cegla, Nael A. McCarty
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Pharmacology
Subjects:
ATPase activity
human ABCC4
human CFTR
lamprey CFTR
Sf9 cell
baculovirus
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1363456/full

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https://www.frontiersin.org/articles/10.3389/fphar.2024.1363456/full

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