Protocol for neurogenin-2-mediated induction of human stem cell-derived neural progenitor cells

Summary: Human pluripotent stem cell-derived neural progenitor cells (NPCs) are an essential tool for the study of brain development and developmental disorders such as autism. Here, we present a protocol to generate NPCs rapidly and reproducibly from human stem cells using dual-SMAD inhibition coup...

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Bibliographic Details
Main Authors: Ellen J. Guss, Laila Sathe, Alexander Dai, Tim Derebenskiy, Ana Rodriguez Vega, Kevin Eggan, Michael F. Wells
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166724000431