Comparison of statistical tests for association between rare variants and binary traits.

Genome-wide association studies have found thousands of common genetic variants associated with a wide variety of diseases and other complex traits. However, a large portion of the predicted genetic contribution to many traits remains unknown. One plausible explanation is that some of the missing va...

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Bibliographic Details
Main Authors: Silviu-Alin Bacanu, Matthew R Nelson, John C Whittaker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3415421?pdf=render