Receptor-mediated drug delivery of bispecific therapeutic antibodies through the blood-brain barrier

Therapeutic antibody drug development is a rapidly growing sector of the pharmaceutical industry. However, antibody drug development for the brain is a technical challenge, and therapeutic antibodies for the central nervous system account for ∼3% of all such agents. The principal obstacle to antibod...

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Bibliographic Details
Main Author: William M. Pardridge
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Drug Delivery
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fddev.2023.1227816/full