A fully human neutralizing monoclonal antibody targeting a highly conserved epitope of the human cytomegalovirus glycoprotein B.

Human cytomegalovirus causes severe diseases in children (by congenital infection) and immunocompromised patients. Treatment with antiviral agents, such as ganciclovir, is limited by their toxicity. In this study, we investigated the effectiveness of a fully human neutralizing monoclonal antibody to...

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Détails bibliographiques
Auteurs principaux: Miwa Okamoto, Rika Kurino, Ryu Miura, Kenzo Takada
Format: Article
Langue:English
Publié: Public Library of Science (PLoS) 2023-01-01
Collection:PLoS ONE
Accès en ligne:https://doi.org/10.1371/journal.pone.0285672