Soluble transforming growth factor beta-1 enhances murine mast cell release of Interleukin 6 in IgE-independent and Interleukin 13 in IgE-dependent settings in vitro.

INTRODUCTION:For immune cells transforming growth factor beta-1 (TGF-β1) can enhance or repress effector functions. Here, we characterize the effects of TGF-β1 on IgE-mediated and IL-33-mediated activation of primary murine mast cells derived from hematopoietic stem cells (bone marrow derived mast c...

Полное описание

Библиографические подробности
Главные авторы: David O Lyons, Michele R Plewes, Nicholas A Pullen
Формат: Статья
Язык:English
Опубликовано: Public Library of Science (PLoS) 2018-01-01
Серии:PLoS ONE
Online-ссылка:http://europepmc.org/articles/PMC6239331?pdf=render