MET genetic abnormalities unreliable for patient selection for therapeutic intervention in oropharyngeal squamous cell carcinoma.

MET genetic abnormalities unreliable for patient selection for therapeutic intervention in oropharyngeal squamous cell carcinoma.

BACKGROUND: Identification of MET genetic alteration, mutation, or amplification in oropharyngeal squamous cell carcinoma (OPSCC) could lead to development of MET selective kinase inhibitors. The aim of this study was to assess the frequency and prognostic value of MET gene mutation, amplification,...

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Main Authors: Ludovic Lacroix, Sophie F Post, Alexander Valent, Antoine E Melkane, Philippe Vielh, Coumaran Egile, Christelle Castell, Christelle Larois, Sandrine Micallef, Patrick Saulnier, Hélène Goulaouic, Anne-Marie Lefebvre, Stéphane Temam
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3894941?pdf=render

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http://europepmc.org/articles/PMC3894941?pdf=render

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