Crystal structure of the human SUV39H1 chromodomain and its recognition of histone H3K9me2/3.

Crystal structure of the human SUV39H1 chromodomain and its recognition of histone H3K9me2/3.

SUV39H1, the first identified histone lysine methyltransferase in human, is involved in chromatin modification and gene regulation. SUV39H1 contains a chromodomain in its N-terminus, which potentially plays a role in methyl-lysine recognition and SUV39H1 targeting. In this study, the structure of th...

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Bibliografski detalji
Glavni autori: Tao Wang, Chao Xu, Yanli Liu, Kai Fan, Zhihong Li, Xing Sun, Hui Ouyang, Xuecheng Zhang, Jiahai Zhang, Yanjun Li, Farrell Mackenzie, Jinrong Min, Xiaoming Tu
Format: Članak
Jezik:English
Izdano: Public Library of Science (PLoS) 2012-01-01
Serija:PLoS ONE
Online pristup:http://europepmc.org/articles/PMC3532415?pdf=render

Internet

http://europepmc.org/articles/PMC3532415?pdf=render

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