Evidence for NADPH oxidase activation by GPR40 in pancreatic β-cells
Objective: Investigate the involvement of the fatty acids receptor GPR40 in the assembly and activation of NADPH oxidase and the implications on pancreatic β-cell function. Methods: BRIN-BD11 β-cells were exposed to GPR40 agonist (GW9508) or linoleic acid in different glucose concentrations. Superox...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2020-01-01
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| Series: | Redox Report |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/13510002.2020.1757877 |