Evidence for NADPH oxidase activation by GPR40 in pancreatic β-cells

Objective: Investigate the involvement of the fatty acids receptor GPR40 in the assembly and activation of NADPH oxidase and the implications on pancreatic β-cell function. Methods: BRIN-BD11 β-cells were exposed to GPR40 agonist (GW9508) or linoleic acid in different glucose concentrations. Superox...

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Бібліографічні деталі
Автори: Gabriela Nunes Marsiglio-Librais, Eloisa Aparecida Vilas-Boas, Christopher Carlein, Markus Daniel Alexander Hoffmann, Leticia Prates Roma, Angelo Rafael Carpinelli
Формат: Стаття
Мова:English
Опубліковано: Taylor & Francis Group 2020-01-01
Серія:Redox Report
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Онлайн доступ:http://dx.doi.org/10.1080/13510002.2020.1757877