MicroRNA-425-5p modulates osteoporosis by targeting annexin A2

Abstract Background Studies have shown that the decrease of osteogenic differentiation of bone marrow mesenchymal stem cells (MSC) is an important mechanism of osteoporosis. The object of this study was to explore the role and mechanism of microRNA miR-425-5p in the differentiation of MSC. Methods T...

Full description

Bibliographic Details
Main Authors: Guanghua Chen, Guizhi Huang, Han Lin, Xinyou Wu, Xiaoyan Tan, Zhoutao Chen
Format: Article
Language:English
Published: BMC 2021-12-01
Series:Immunity & Ageing
Subjects:
Online Access:https://doi.org/10.1186/s12979-021-00256-7