Enhanced medullary and extramedullary granulopoiesis sustain the inflammatory response in lupus nephritis
Objectives In SLE, deregulation of haematopoiesis is characterised by inflammatory priming and myeloid skewing of haematopoietic stem and progenitor cells (HSPCs). We sought to investigate the role of extramedullary haematopoiesis (EMH) as a key player for tissue injury in systemic autoimmune disord...
Main Authors: | , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMJ Publishing Group
2024-03-01
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Series: | Lupus Science and Medicine |
Online Access: | https://lupus.bmj.com/content/11/1/e001110.full |