Endothelial Cell-Specific Molecule 1 Promotes Endothelial to Mesenchymal Transition in Renal Fibrosis

Endothelial Cell-Specific Molecule 1 Promotes Endothelial to Mesenchymal Transition in Renal Fibrosis

The endothelial-to-mesenchymal transition (EndoMT) is involved in the complex pathogenesis of renal fibrosis. The soluble proteoglycan endothelial cell-specific molecule 1 (ESM1) is significantly upregulated in many tumor cells and cirrhosis-related disease. The role of ESM1 in renal fibrosis is unk...

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Bibliographic Details
Main Authors: Tung-Wei Hung, Chao-Yang Chu, Chen-Lin Yu, Chu-Che Lee, Li-Sung Hsu, Yong-Syuan Chen, Yi-Hsien Hsieh, Jen-Pi Tsai
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Toxins
Subjects:
endothelial-to-mesenchymal transition
renal fibrosis
endothelial cell specific molecule 1
motility
migration
unilateral ureter obstruction
Online Access:https://www.mdpi.com/2072-6651/12/8/506

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https://www.mdpi.com/2072-6651/12/8/506

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