Quantitative contributions of TNF receptor superfamily members to CD8+ T‐cell responses

Quantitative contributions of TNF receptor superfamily members to CD8+ T‐cell responses

Abstract T‐cell responses to infections and cancers are regulated by co‐signalling receptors grouped into the binary categories of co‐stimulation or co‐inhibition. The co‐stimulation TNF receptor superfamily (TNFRSF) members 4‐1BB, CD27, GITR and OX40 have similar signalling mechanisms raising the q...

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Bibliographic Details
Main Authors: John Nguyen, Johannes Pettmann, Philipp Kruger, Omer Dushek
Format: Article
Language:English
Published: Springer Nature 2021-11-01
Series:Molecular Systems Biology
Subjects:
co‐stimulation
modelling
quantitative phenotypes
T cells
tumour necrosis factor receptor superfamily
Online Access:https://doi.org/10.15252/msb.202110560

Internet

https://doi.org/10.15252/msb.202110560

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