TREM2 in Alzheimer’s Disease: Microglial Survival and Energy Metabolism

TREM2 in Alzheimer’s Disease: Microglial Survival and Energy Metabolism

Alzheimer’s disease (AD) is the leading cause of age-related dementia among the elderly population. Recent genetic studies have identified rare variants of the gene encoding the triggering receptor expressed on myeloid cells-2 (TREM2) as significant genetic risk factors in late-onset AD (LOAD). TREM...

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Bibliographic Details
Main Authors: Honghua Zheng, Baoying Cheng, Yanfang Li, Xin Li, Xiaofen Chen, Yun-wu Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Aging Neuroscience
Subjects:
Alzheimer’s disease
TREM2
microglia
survival
metabolism
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2018.00395/full

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https://www.frontiersin.org/article/10.3389/fnagi.2018.00395/full

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