Validation of epigenetic markers to identify colitis associated cancer: Results of module 1 of the ENDCAP-C studyResearch in context

Background: Chronic inflammation caused by ulcerative colitis (UC) causes a pro-neoplastic drive in the inflamed colon, leading to a markedly greater risk of invasive malignancy compared to the general population. Despite surveillance protocols, 50% of cases proceed to cancer before neoplasia is det...

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Bibliographic Details
Main Authors: Andrew D. Beggs, Samir Mehta, Jonathan J. Deeks, Jonathan D. James, Germaine M. Caldwell, Mark P. Dilworth, Joanne D. Stockton, Daniel Blakeway, Valerie Pestinger, Alexandra Vince, Phillipe Taniere, Tariq Iqbal, Laura Magill, Glenn Matthews, Dion G. Morton
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396418305383