Pancreatic draining lymph nodes (PLNs) serve as a pathogenic hub contributing to the development of type 1 diabetes

Pancreatic draining lymph nodes (PLNs) serve as a pathogenic hub contributing to the development of type 1 diabetes

Abstract Type 1 diabetes (T1D) is a chronic, progressive autoinflammatory disorder resulting from the breakdown of self-tolerance and unrestrained β cell-reactive immune response. Activation of immune cells is initiated in islet and amplified in lymphoid tissues, especially those pancreatic draining...

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Bibliographic Details
Main Authors: Fei Sun, Chun-Liang Yang, Fa-Xi Wang, Shan-Jie Rong, Jia-Hui Luo, Wan-Ying Lu, Tian-Tian Yue, Cong-Yi Wang, Shi-Wei Liu
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Cell & Bioscience
Subjects:
Type 1 diabetes (T1D)
Pancreatic draining lymph nodes (PLNs)
Signal inputs
PLN remodeling
Signal outputs
Online Access:https://doi.org/10.1186/s13578-023-01110-7

Internet

https://doi.org/10.1186/s13578-023-01110-7

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