Multi-Modal PET and MR Imaging in the Hen’s Egg Test-Chorioallantoic Membrane (HET-CAM) Model for Initial In Vivo Testing of Target-Specific Radioligands

Multi-Modal PET and MR Imaging in the Hen’s Egg Test-Chorioallantoic Membrane (HET-CAM) Model for Initial In Vivo Testing of Target-Specific Radioligands

The validation of novel target-specific radioligands requires animal experiments mostly using mice with xenografts. A pre-selection based on a simpler in vivo model would allow to reduce the number of animal experiments, in accordance with the 3Rs principles (reduction, replacement, refinement). In...

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Bibliographic Details
Main Authors: Gordon Winter, Andrea B. F. Koch, Jessica Löffler, Mika Lindén, Christoph Solbach, Alireza Abaei, Hao Li, Gerhard Glatting, Ambros J. Beer, Volker Rasche
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Cancers
Subjects:
PSMA
HET-CAM
chick embryo
PET
MRI
multi-modal imaging
Online Access:https://www.mdpi.com/2072-6694/12/5/1248

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https://www.mdpi.com/2072-6694/12/5/1248

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