Globally invariant behavior of oncogenes and random genes at population but not at single cell level

Abstract Cancer is widely considered a genetic disease. Notably, recent works have highlighted that every human gene may possibly be associated with cancer. Thus, the distinction between genes that drive oncogenesis and those that are associated to the disease, but do not play a role, requires atten...

Full description

Bibliographic Details
Main Authors: Olga Sirbu, Mohamed Helmy, Alessandro Giuliani, Kumar Selvarajoo
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:npj Systems Biology and Applications
Online Access:https://doi.org/10.1038/s41540-023-00290-9