KRAS in NSCLC: State of the Art and Future Perspectives

In NSCLC, KRAS mutations occur in up to 30% of all cases, most frequently at codon 12 and 13. KRAS mutations have been linked to adenocarcinoma histology, positive smoking history, and Caucasian ethnicity, although differences have been described across KRAS mutational variants subtypes. KRAS mutati...

Full description

Bibliographic Details
Main Authors: Priscilla Cascetta, Arianna Marinello, Chiara Lazzari, Vanesa Gregorc, David Planchard, Roberto Bianco, Nicola Normanno, Alessandro Morabito
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/14/21/5430