Variant Analysis of the Thymidine Kinase and DNA Polymerase Genes of Herpes Simplex Virus in Korea: Frequency of Acyclovir Resistance Mutations

Variant Analysis of the Thymidine Kinase and DNA Polymerase Genes of Herpes Simplex Virus in Korea: Frequency of Acyclovir Resistance Mutations

The thymidine kinase (TK) and DNA polymerase (pol) genes of the herpes simplex viruses type 1 (HSV-1) and type 2 (HSV-2) are two important genes involved in antiviral resistance. We investigated the genetic polymorphisms of the HSV-TK and pol genes in clinical isolates from Korean HSV-infected patie...

Full description

Bibliographic Details
Main Authors: Jungwon Hyun, Su Kyung Lee, Ji Hyun Kim, Eun-Jung Cho, Han-Sung Kim, Jae-Seok Kim, Wonkeun Song, Hyun Soo Kim
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Viruses
Subjects:
HSV-1
HSV-2
antiviral resistance
variants
next-generation sequencing
polymorphisms
Online Access:https://www.mdpi.com/1999-4915/15/8/1709

Internet

https://www.mdpi.com/1999-4915/15/8/1709

Similar Items