Long-lasting masculinizing effects of postnatal androgens on myelin governed by the brain androgen receptor.

The oligodendrocyte density is greater and myelin sheaths are thicker in the adult male mouse brain when compared with females. Here, we show that these sex differences emerge during the first 10 postnatal days, precisely at a stage when a late wave of oligodendrocyte progenitor cells arises and sta...

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Bibliographic Details
Main Authors: Charly Abi Ghanem, Cindy Degerny, Rashad Hussain, Philippe Liere, Antoine Pianos, Sophie Tourpin, René Habert, Wendy B Macklin, Michael Schumacher, Abdel M Ghoumari
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-11-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC5690690?pdf=render