Regulators, functions, and mechanotransduction pathways of matrix stiffness in hepatic disease
The extracellular matrix (ECM) provides physical support and imparts significant biochemical and mechanical cues to cells. Matrix stiffening is a hallmark of liver fibrosis and is associated with many hepatic diseases, especially liver cirrhosis and carcinoma. Increased matrix stiffness is not only...
Hlavní autoři: | , , , , , |
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Médium: | Článek |
Jazyk: | English |
Vydáno: |
Frontiers Media S.A.
2023-01-01
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Edice: | Frontiers in Physiology |
Témata: | |
On-line přístup: | https://www.frontiersin.org/articles/10.3389/fphys.2023.1098129/full |