Evaluation of the Sleep-Prolonging Effect of Lagenaria vulgaris and Cucurbita pepo Extracts on Pentobarbital-Induced Sleep and Possible Mechanisms of Action

Evaluation of the Sleep-Prolonging Effect of Lagenaria vulgaris and Cucurbita pepo Extracts on Pentobarbital-Induced Sleep and Possible Mechanisms of Action

Introduction: Sleeplessness is the most common sleep disorder. In this study, the hypnotic effect of macerated (HAME) and soxhlet (HASE) extract of Lagenaria vulgaris (fruit and seed) and Cucurbita pepo (fruit) were studied in mice. Methods: Extracts and fractions were administered intra-peritoneall...

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Bibliographic Details
Main Authors: Vafa Baradaran Rahimi, Vahid Reza Askari, Amineh Sadat Tajani, Azar Hosseini, Hassan Rakhshandeh
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Medicina
Subjects:
insomnia
Lagenaria vulgaris
Cucurbita pepo
flumazenil
naloxone
Online Access:http://www.mdpi.com/1010-660X/54/4/55

Internet

http://www.mdpi.com/1010-660X/54/4/55

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