Sex-dependent treatment of chronic EAE with partial MHC class II constructs

Sex-dependent treatment of chronic EAE with partial MHC class II constructs

Abstract Background One of the main challenges in treating multiple sclerosis (MS) is reversing the effects of accumulated damage in the central nervous system (CNS) of progressive MS subjects. While most of the available drugs for MS subjects are anti-inflammatory and thus are limited to relapsing-...

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Bibliographic Details
Main Authors: Gil Benedek, Priya Chaudhary, Roberto Meza-Romero, Evan Calkins, Gail Kent, Halina Offner, Dennis Bourdette, Arthur A. Vandenbark
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Journal of Neuroinflammation
Subjects:
Chronic experimental autoimmune encephalomyelitis (EAE)
Multiple sclerosis (MS)
RTL342M
DRα1-mMOG-35-55
Gender effect
Online Access:http://link.springer.com/article/10.1186/s12974-017-0873-y

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http://link.springer.com/article/10.1186/s12974-017-0873-y

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