The PI3K/AKT/mTOR signaling pathway is overactivated in primary aldosteronism.

The PI3K/AKT/mTOR signaling pathway is overactivated in primary aldosteronism.

BACKGROUND: To date, the available non-invasive remedies for primary aldosteronism are not satisfactory in clinical practice. The phosphoinositide 3-kinase (PI3Ks)/protein kinase B (PKB or AKT)/mammalian target of rapamycin (mTOR) signaling pathway is essential for tumorigenesis and metastasis in ma...

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Bibliographic Details
Main Authors: Hengchuan Su, Yanyun Gu, Fengying Li, Qidi Wang, Baoxing Huang, Xiaolong Jin, Guang Ning, Fukang Sun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3633845?pdf=render

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http://europepmc.org/articles/PMC3633845?pdf=render

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