Transient Receptor Potential Ankyrin 1 Mediates Hypoxic Responses in Mice

Transient Receptor Potential Ankyrin 1 Mediates Hypoxic Responses in Mice

Transient receptor potential ankyrin 1 (TRPA1) is a non-selective cation channel that is broadly expressed in sensory pathways, such as the trigeminal and vagus nerves. It is capable of detecting various irritants in inspired gasses and is activated during hypoxia. In this study, the role of TRPA1 i...

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Bibliographic Details
Main Authors: Sichong Chen, Nobuaki Takahashi, Changping Chen, Jordan L. Pauli, Chiharu Kuroki, Jun Kaminosono, Hideki Kashiwadani, Yuichi Kanmura, Yasuo Mori, Shaowu Ou, Liying Hao, Tomoyuki Kuwaki
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Physiology
Subjects:
transient receptor potential ankyrin-1
avoidance behavior
hypoxic arousal
respiratory chemoreflex
trigeminal afferent nerve
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2020.576209/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2020.576209/full

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