The β-blocker carvedilol and the benznidazole modulate the cardiac immune response in the acute infection induced by Colombian strain of the Trypanosoma cruzi

The β-blocker carvedilol and the benznidazole modulate the cardiac immune response in the acute infection induced by Colombian strain of the Trypanosoma cruzi

BACKGROUND The infection led by Trypanosoma cruzi persists in mammalian tissues causing an inflammatory imbalance. Carvedilol (Cv), a non-selective beta blocker drug indicated to treat heart failure and antihypertensive has shown to promote antioxidant and immunomodulatory properties which might imp...

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Bibliographic Details
Main Authors: Aline Luciano Horta, Vivian Paulino Figueiredo, Ana Luisa Junqueira Leite, Guilherme de Paula Costa, Ana Paula de Jesus Menezes, Camila de Oliveira Ramos, Tamiles Caroline Fernandes Pedrosa, Frank Silva Bezerra, Paula Melo de Abreu Vieira, André Talvani
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2018-10-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
carvedilol
Trypanosoma cruzi
inflammation
heart disease
chemokines
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762018001100301&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762018001100301&lng=en&tlng=en

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