Evolocumab loaded Bio-Liposomes for efficient atherosclerosis therapy

Evolocumab loaded Bio-Liposomes for efficient atherosclerosis therapy

Abstract PCSK9, which is closely related to atherosclerosis, is significantly expressed in vascular smooth muscle cells (VSMCs). Moreover, Proprotein Convertase Subtilisin/Kexin type 9 (PCSK9) mediated phenotypic transformation, abnormal proliferation, and migration of VSMCs play key roles in accele...

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Bibliographic Details
Main Authors: Zhenxian Li, Haimei Zhu, Hao Liu, Dayue Liu, Jianhe Liu, Jiazheng Jiang, Yi Zhang, Zhang Qin, Yijia Xu, Yuan Peng, Bin Liu, Yun Long
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Journal of Nanobiotechnology
Subjects:
Atherosclerosis
Evolocumab
Proprotein convertase subtilisin/Kexin type 9
Liposome
Phenotypic transition
Online Access:https://doi.org/10.1186/s12951-023-01904-4

Internet

https://doi.org/10.1186/s12951-023-01904-4

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