Bioequivalence evaluation and food effect assessment of Lisinopril/amlodipine tablets in healthy Chinese subjects under fasting and fed conditions

Bioequivalence evaluation and food effect assessment of Lisinopril/amlodipine tablets in healthy Chinese subjects under fasting and fed conditions

Abstract Purpose The combination of lisinopril and amlodipine has a marked additional effect on blood pressure and fewer side effects than individual monotherapy. This study was conducted to compare the pharmacokinetic parameters and evaluate the bioequivalence between two Lisinopril/amlodipine tabl...

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Bibliographic Details
Main Authors: Ting Li, Yan-ping Liu, Shu-qin Liu, Ping Shi, Xin Jiang, Ye Tao, Xiao-meng Gao, Ya-ping Ma, Yu Cao
Format: Article
Language:English
Published: BMC 2022-07-01
Series:BMC Pharmacology and Toxicology
Subjects:
Lisinopril
Amlodipine
Bioequivalence
Pharmacokinetic
Food effect
Online Access:https://doi.org/10.1186/s40360-022-00590-6

Internet

https://doi.org/10.1186/s40360-022-00590-6

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