Immunogenicity and Protective Ability of Genotype I-Based Recombinant Japanese Encephalitis Virus (JEV) with Attenuation Mutations in E Protein against Genotype V JEV

Immunogenicity and Protective Ability of Genotype I-Based Recombinant Japanese Encephalitis Virus (JEV) with Attenuation Mutations in E Protein against Genotype V JEV

Genotype V (GV) Japanese encephalitis virus (JEV) has emerged in Korea and China since 2009. Recent findings suggest that current Japanese encephalitis (JE) vaccines may reduce the ability to induce neutralizing antibodies against GV JEV compared to other genotypes. This study sought to produce a no...

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Bibliographic Details
Main Authors: Shigeru Tajima, Satoshi Taniguchi, Eri Nakayama, Takahiro Maeki, Takuya Inagaki, Masayuki Saijo, Chang Kweng Lim
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Vaccines
Subjects:
Japanese encephalitis virus
genotype V
reverse genetics
live attenuated vaccine
Online Access:https://www.mdpi.com/2076-393X/9/10/1077

Internet

https://www.mdpi.com/2076-393X/9/10/1077

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