Model-based whole-brain perturbational landscape of neurodegenerative diseases

Model-based whole-brain perturbational landscape of neurodegenerative diseases

The treatment of neurodegenerative diseases is hindered by lack of interventions capable of steering multimodal whole-brain dynamics towards patterns indicative of preserved brain health. To address this problem, we combined deep learning with a model capable of reproducing whole-brain functional co...

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Bibliographic Details
Main Authors: Yonatan Sanz Perl, Sol Fittipaldi, Cecilia Gonzalez Campo, Sebastián Moguilner, Josephine Cruzat, Matias E Fraile-Vazquez, Rubén Herzog, Morten L Kringelbach, Gustavo Deco, Pavel Prado, Agustin Ibanez, Enzo Tagliazucchi
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-03-01
Series:eLife
Subjects:
neurodegeneration
fMRI
whole-brain computational modelling
deep learning
Online Access:https://elifesciences.org/articles/83970

Internet

https://elifesciences.org/articles/83970

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