Forensic toxicokinetics of difenidol hydrochloride in vivo verified by practical lethal cases

Abstract A gas chromatography-mass spectrometry (GC–MS) method for the determination of difenidol hydrochloride in biological specimens has been developed. The method exhibited excellent recovery (> 90%) and precision (RSD < 10%), and the LOD was 0.05 μg/mL or μg/g, which met the requirements...

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Bibliographic Details
Main Authors: Weifen Niu, Tongxi Ren, Yandan Wang, Zheyu Wang, Chao Zhang, Juan Jia, Zhiwen Wei, Hongliang Su, Zhongyuan Guo, Xiangjie Guo, Keming Yun
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-38246-y