LASSI-L detects early cognitive changes in pre-motor manifest Huntington’s disease: a replication and validation study

LASSI-L detects early cognitive changes in pre-motor manifest Huntington’s disease: a replication and validation study

Background and objectivesCognitive decline is an important early sign in pre-motor manifest Huntington’s disease (preHD) and is characterized by deficits across multiple domains including executive function, psychomotor processing speed, and memory retrieval. Prior work suggested that the Loewenstei...

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Bibliographic Details
Main Authors: Luis A. Sierra, Shelby B. Hughes, Clementina J. Ullman, Andrew Hall, Sarbesh R. Pandeya, Robin Schubert, Samuel A. Frank, Mark A. Halko, Jody Corey-Bloom, Simon Laganiere
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Neurology
Subjects:
semantic interference
cognitive
Huntington disease
executive function
pre-motor manifest HD
LASSI-L
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2023.1191718/full

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https://www.frontiersin.org/articles/10.3389/fneur.2023.1191718/full

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