Assessment of DNA interstrand crosslinks in NIH/3T3 cells induced by Chloroethylnitrosoureas
Aim: To investigated the mechanism of Chloroethylnitrosoureas (CENUs) leading to secondary tumors after therapy, three kinds of CENUs, namely, Nimustine (ACNU), Carmustine (BCNU) and Semustine (MeCCNU) were used to investigated drug-induced DNA interstrand crosslinks(ICLs). Method: The alkaline come...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
EDP Sciences
2017-01-01
|
Series: | BIO Web of Conferences |
Online Access: | http://dx.doi.org/10.1051/bioconf/20170801019 |