Salvianolic acid B attenuates tubulointerstitial fibrosis by inhibiting EZH2 to regulate the PTEN/Akt pathway

Salvianolic acid B attenuates tubulointerstitial fibrosis by inhibiting EZH2 to regulate the PTEN/Akt pathway

AbstractContext Salvianolic acid B (SAB) can alleviate renal fibrosis and improve the renal function.Objective To investigate the effect of SAB on renal tubulointerstitial fibrosis and explore its underlying mechanisms.Materials and methods Male C57 mice were subjected to unilateral ureteric obstruc...

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Bibliographic Details
Main Authors: Pinglan Lin, Furong Qiu, Ming Wu, Lin Xu, Di Huang, Chen Wang, Xuejun Yang, Chaoyang Ye
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Pharmaceutical Biology
Subjects:
Renal fibrosis
chronic kidney diseases
ureteral unilateral obstruction
Aristolochic acid nephropathy
transforming growth factor-β
Online Access:https://www.tandfonline.com/doi/10.1080/13880209.2022.2148169

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https://www.tandfonline.com/doi/10.1080/13880209.2022.2148169

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