Combination Chemotherapy with Cisplatin and Chloroquine: Effect of Encapsulation in Micelles Formed by Self-Assembling Hybrid Dendritic–Linear–Dendritic Block Copolymers

Combination Chemotherapy with Cisplatin and Chloroquine: Effect of Encapsulation in Micelles Formed by Self-Assembling Hybrid Dendritic–Linear–Dendritic Block Copolymers

Clinical outcomes of conventional drug combinations are not ideal due to high toxicity to healthy tissues. Cisplatin (CDDP) is the standard component for many cancer treatments, yet its principal dose-limiting side effect is nephrotoxicity. Thus, CDDP is commonly used in combination with other drugs...

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Bibliographic Details
Main Authors: Rebeca González-Pastor, Alexandre Lancelot, Violeta Morcuende-Ventura, María San Anselmo, Teresa Sierra, José L. Serrano, Pilar Martin-Duque
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
chloroquine
cisplatin
combination chemotherapy
encapsulation
hybrid dendritic–linear–dendritic block copolymers
Online Access:https://www.mdpi.com/1422-0067/22/10/5223

Internet

https://www.mdpi.com/1422-0067/22/10/5223

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