Synthesis, X-ray diffraction study, analysis of intermolecular interactions and molecular docking of ethyl 1-(3-tosylquinolin-4-yl)piperidine-4-carboxylate

Synthesis, X-ray diffraction study, analysis of intermolecular interactions and molecular docking of ethyl 1-(3-tosylquinolin-4-yl)piperidine-4-carboxylate

The title compound, C24H26N2O4S, can be obtained via two synthetic routes. According to our investigations, the most suitable way is by the reaction of ethyl 2-bromoacetate with sodium tosylsulfinate in dry DMF. It was crystallized from methanol into the monoclinic P21/n space group with a single mo...

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Bibliographic Details
Main Authors: Yevhenii Vaksler, Halyna V. Hryhoriv, Sergiy M. Kovalenko, Lina O. Perekhoda, Victoriya A. Georgiyants
Format: Article
Language:English
Published: International Union of Crystallography 2022-09-01
Series:Acta Crystallographica Section E: Crystallographic Communications
Subjects:
ethyl 1-(3-tosylquinolin-4-yl)piperidine-4-carboxylate
antibacterial properties
molecular and crystal structure
hirshfeld surface analysis
pairwise interaction energy
molecular docking
Online Access:http://scripts.iucr.org/cgi-bin/paper?S2056989022007691

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http://scripts.iucr.org/cgi-bin/paper?S2056989022007691

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