IFI16 Impacts Metabolic Reprogramming during Human Cytomegalovirus Infection

IFI16 Impacts Metabolic Reprogramming during Human Cytomegalovirus Infection

ABSTRACT Cellular lipid metabolism plays a pivotal role in human cytomegalovirus (HCMV) infection, as increased lipogenesis in HCMV-infected cells favors the envelopment of newly synthesized viral particles. As all cells are equipped with restriction factors (RFs) able to exert a protective effect a...

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Bibliographic Details
Main Authors: Gloria Griffante, Weronika Hewelt-Belka, Camilla Albano, Francesca Gugliesi, Selina Pasquero, Sergio Fernando Castillo Pacheco, Greta Bajetto, Paolo Ettore Porporato, Erica Mina, Marta Vallino, Christian Krapp, Martin Roelsgaard Jakobsen, John Purdy, Jens von Einem, Santo Landolfo, Valentina Dell’Oste, Matteo Biolatti
Format: Article
Language:English
Published: American Society for Microbiology 2022-06-01
Series:mBio
Subjects:
IFI16
glucose and lipid metabolism
human cytomegalovirus
lipidomics
virus-host interactions
Online Access:https://journals.asm.org/doi/10.1128/mbio.00435-22

Internet

https://journals.asm.org/doi/10.1128/mbio.00435-22

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