Pseudomonas Acts as a Reservoir of Novel Tigecycline Resistance Efflux Pump tmexC6D6-toprJ1b and tmexCD-toprJ Variants

Pseudomonas Acts as a Reservoir of Novel Tigecycline Resistance Efflux Pump tmexC6D6-toprJ1b and tmexCD-toprJ Variants

ABSTRACT Several variants of the plasmid-carried tigecycline resistance gene cluster, tmexCD-toprJ, have been identified. This study characterized another novel variant, tmexC6D6-toprJ1b, located on the chromosome of environmental-origin Pseudomonas mendocina. TMexC6D6-TOprJ1 mediates resistance to...

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Bibliographic Details
Main Authors: Cheng-Zhen Wang, Xun Gao, Xin-Hong Liang, Lu-Chao Lv, Li-Tao Lu, Chao Yue, Xiao-Xiao Cui, Ke-Er Yang, Duo Lu, Jian-Hua Liu, Jun Yang
Format: Article
Language:English
Published: American Society for Microbiology 2023-06-01
Series:Microbiology Spectrum
Subjects:
Pseudomonas
tigecycline resistance
efflux pump
tmexCD-toprJ
transcription regulator
promoter
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00767-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.00767-23

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