Structure of Alcohol Oxidase from Pichia pastoris by Cryo-Electron Microscopy.

The first step in methanol metabolism in methylotrophic yeasts, the oxidation of methanol and higher alcohols with molecular oxygen to formaldehyde and hydrogen peroxide, is catalysed by alcohol oxidase (AOX), a 600-kDa homo-octamer containing eight FAD cofactors. When these yeasts are grown with me...

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Bibliographic Details
Main Authors: Janet Vonck, David N Parcej, Deryck J Mills
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4961394?pdf=render