Human Endogenous Retrovirus K in the Crosstalk Between Cancer Cells Microenvironment and Plasticity: A New Perspective for Combination Therapy

Human Endogenous Retrovirus K in the Crosstalk Between Cancer Cells Microenvironment and Plasticity: A New Perspective for Combination Therapy

Abnormal activation of human endogenous retroviruses (HERVs) has been associated with several diseases such as cancer, autoimmunity, and neurological disorders. In particular, in cancer HERV activity and expression have been specifically associated with tumor aggressiveness and patient outcomes. Can...

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Bibliographic Details
Main Authors: Emanuela Balestrieri, Ayele Argaw-Denboba, Alessandra Gambacurta, Chiara Cipriani, Roberto Bei, Annalucia Serafino, Paola Sinibaldi-Vallebona, Claudia Matteucci
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Microbiology
Subjects:
endogenous retroviruses
cancer plasticity
cancer therapy
cancer biomarker
combination therapy
reprogramming
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.01448/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2018.01448/full

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