Behavioral analysis through the lifespan of disc1 mutant zebrafish identifies defects in sensorimotor transformation

Summary: DISC1 is a genetic risk factor for multiple psychiatric disorders. Compared to the dozens of murine Disc1 models, there is a paucity of zebrafish disc1 models—an organism amenable to high-throughput experimentation. We conducted the longitudinal neurobehavioral analysis of disc1 mutant zebr...

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Bibliographic Details
Main Authors: Brock R. Pluimer, Devin L. Harrison, Chanon Boonyavairoje, Eric P. Prinssen, Mark Rogers-Evans, Randall T. Peterson, Summer B. Thyme, Anjali K. Nath
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223011768