The Nav1.9 Channel Is a Key Determinant of Cold Pain Sensation and Cold Allodynia

Cold-triggered pain is essential to avoid prolonged exposure to harmfully low temperatures. However, the molecular basis of noxious cold sensing in mammals is still not completely understood. Here, we show that the voltage-gated Nav1.9 sodium channel is important for the perception of pain in respon...

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Bibliographic Details
Main Authors: Stéphane Lolignier, Caroline Bonnet, Christelle Gaudioso, Jacques Noël, Jérôme Ruel, Muriel Amsalem, Jérémy Ferrier, Lise Rodat-Despoix, Valentine Bouvier, Youssef Aissouni, Laetitia Prival, Eric Chapuy, Françoise Padilla, Alain Eschalier, Patrick Delmas, Jérôme Busserolles
Format: Article
Language:English
Published: Elsevier 2015-05-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715004143