Molecular Simulation-Based Investigation of Highly Potent Natural Products to Abrogate Formation of the nsp10–nsp16 Complex of SARS-CoV-2

The SARS-CoV-2 non-structural protein (nsp) nsp10–nsp16 complex is essential for the 2′-O-methylation of viral mRNA, a crucial step for evading the innate immune system, and it is an essential process in SARS-CoV-2 life cycle. Therefore, detecting molecules that can disrupt the nsp10–nsp16 interacti...

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Bibliographic Details
Main Authors: Anwar Mohammad, Eman Alshawaf, Sulaiman K. Marafie, Mohamed Abu-Farha, Fahd Al-Mulla, Jehad Abubaker
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/11/4/573